xtt proliferation kit ka1387 (Abnova)
Structured Review

Xtt Proliferation Kit Ka1387, supplied by Abnova, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/xtt proliferation kit ka1387/product/Abnova
Average 90 stars, based on 1 article reviews
Images
1) Product Images from "The biotoxin BMAA promotes dysfunction via distinct mechanisms in neuroblastoma and glioblastoma cells"
Article Title: The biotoxin BMAA promotes dysfunction via distinct mechanisms in neuroblastoma and glioblastoma cells
Journal: bioRxiv
doi: 10.1101/2022.11.24.517806
Figure Legend Snippet: Treatment with increasing doses of BMAA resulted in decreased cell number and inhibition of cell proliferation as measured by XTT assay . Although proliferative inhibition trended with increased BMAA dose, statistical significance was not observed at concentrations less than 4uM . These findings support the hypothesis that while BMAA may be capable of exhibiting repression of proliferative cells, it may cause cellular defects via additional processes, especially at low concentrations.
Techniques Used: Inhibition, XTT Assay
Figure Legend Snippet: Cell number is enhanced in the glioblastoma cell line U118MG by BMAA treatment for 7 days (A). XTT assay shows BMAA induces proliferation over a 7 day incubation period (B). BMAA does not increase cytotoxicity in U118MG cells, even at 25uM doses. Cell lysis in response to BMAA was measured by a fluorescence-based LDH cytotoxicity assay (C).
Techniques Used: XTT Assay, Incubation, Lysis, Fluorescence, LDH Cytotoxicity Assay